Opioid Replacement Therapy (ORT)

Opioid replacement therapy (ORT), also called opioid substitution therapy or opioid maintenance therapy, involves replacing an opioid, such as heroin, with a longer acting but less euphoric opioid. Commonly used drugs for ORT are methadone or buprenorphine which are taken under medical supervision.

The Food and Drug Administration (FDA) has approved three medications for use in the treatment of opioid dependence: methadone, naltrexone, and buprenorphine.

Opioid substitution treatment explained

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